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Significance Statement Although potentiating resilience is foundational to crop improvement, and despite the notion that cell wall (CW) protects against pathogens, the extent of pathogen‐induced CW changes and the CW composition requirements for a successful defense are largely unknown. By investigating the bacteria‐induced impact on the Arabidopsis CW, we found changes exclusively in infected leaves with the remodeling of distinct CW polysaccharides, including arabinogalactan proteins, whose loss is detrimental to defense, highlighting specific requirements for antagonizing pathogens and potentiating plant defenses.more » « less
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